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ACROBiosystems Human B7-H4 Protein, His Tag
326.60€ - 2181.73€
Specifications
| Accession Number | NP_078902 |
|---|---|
| Molecular Weight (g/mol) | 26.4 kDa |
| Source | Human B7-H4, His Tag (B74-H5222) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # NP_078902). |
| Immunogen | Phe 29 - Ala 258 |
| Storage Requirements | -20°C |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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15805967
|
ACROBiosystems
B74-H5222-100UG |
100 μg |
326.60€
100µg |
Estimated Shipment: 30-04-2024
Log in to see stock. |
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|
15815967
|
ACROBiosystems
B74-H5222-1MG |
1 mg |
2181.73€
1mg |
Estimated Shipment: 30-04-2024
Log in to see stock. |
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Description
V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.4 kDa. The protein migrates as 43-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_078902 | |
| Human B7-H4, His Tag (B74-H5222) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # NP_078902). | |
| -20°C | |
| B7-H4 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 26.4 kDa | |
| Phe 29 - Ala 258 | |
| B7-H4,VTCN1,B7S1,B7h0.5 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |