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Tocris Bioscience™ DPNB-ABT 594

Product Code. 18728246
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 18728246

Brand: Tocris Bioscience™ 6706/5

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This item is not returnable. View return policy

Description

Caged ABT 594 (Cat. No. 6576); suitable for one- or two-photon photolysis

DPNB-ABT 594 is a nitrobenzyl-caged ABT 594 (Cat. No. 6576), a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+ transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination with appropriate two photon pulse laser at 710 nm for ∽2 ms.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-(((2 R)-1-(1-(4,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-2-nitrophenyl)ethyl)azetidin-2-yl)methoxy)-2-chloropyridine
Quantity 5 mg
Target Nicotinic (a4b2) Receptor Agonists
Molecular Formula C31H46ClN3O11
Formula Weight 672.16
Purity 98%
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