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CD45 Rat anti-Mouse, PE-Cy5, Clone: 30-F11, BD

Rat Monoclonal Antibody

139.00€ - 395.00€

Specifications

Antigen CD45
Clone 30-F11
Concentration 0.2mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15851419
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BD Biosciences
561870
25 μg
139.00€
Each
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Estimated Shipment: 22-05-2024
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15816988
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BD Biosciences
553082
0.1 mg
395.00€
Each
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Estimated Shipment: 22-05-2024
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Description

Description

The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific.

Specifications

Specifications

CD45
0.2mg/mL
Monoclonal
Rat
Mouse
IgG2b κ
Affinity Purified
Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
30-F11
Flow Cytometry
PE-Cyanine5
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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