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ACROBiosystems Biotinylated Rat FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (SPR verified)
Biotinylated Protein
Brand: ACROBiosystems FCM-R82W7-200UG
Additional Details : Weight : 0.00001kg
Description
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Biotinylated Rat FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag (SPR verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 34.7 kDa (FCGRT) and 13.1 kDa (B2M). Subunit FCGRT is fused with an Avi tag (Avitag™) at the C-tSpecifications
| NP_203502.1 (FCGRT) and NP_036644.1 (B2M) | |
| 200 μg | |
| Ala 23 - Ser 298 (FCGRT) and Ile 21 - Met 119 (B2M) | |
| FcRn,FCGRT and B2M | |
| Precision Avi | |
| His Tag and Strep Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 34.7 kDa (FCGRT), 13.1 kDa (B2M) | |
| MABSol™ Biotinylated Rat FCGRT&B2M; Heterodimer Protein, Avitag,His Tag&Strep; II Tag (SPR verified) (FCM-R82W7) is expressed from human HEK293 cells. It contains AA Ala 23 - Ser 298 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P13599-1 (FCGRT) and P07151-1 (B2M)). | |
| -20°C | |
| FcRn (FCGRT and B2M) | |
| Rat | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |