missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Biotinylated Mouse M-CSF R / CSF1R / CD115 Protein, Avitag™,His Tag

Biotinylated Protein

Brand:  ACROBiosystems CSR-M82E8-200UG

Additional Details : Weight : 0.00001kg

 View more versions of this product

Product Code. 15816507

  • 1995.26€ / 200µg
Estimated Shipment: 11-04-2024
to see stock.
Add to basket

Description

Description

Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the typeIII subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation . Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 58.4 kDa. The protein migrates as 78-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001032948.2
200 μg
Ala 20 - Ser 511
CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Precision Avi
His Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
58.4 kDa
Biotinylated Mouse M-CSF R, Avitag,His Tag (CSR-M82E8) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Ser 511 (Accession # P09581-1).
-20°C
M-CSF R
Mouse
PBS, pH7.4
HEK293
MABSol™ Biotin Labeled Proteins
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers