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ACROBiosystems Biotinylated Human TSLP Protein, His, Avitag™
Biotinylated Protein
Brand: ACROBiosystems TSP-H82EB-200UG
Additional Details : Weight : 0.00001kg
Description
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 18.6 kDa. As a result of glycosylation, the protein migrates as 11 kDa and 18-21 kDa under reducing (R) condition, and 22-28 kDa under nSpecifications
| NP_149024.1 | |
| 200 μg | |
| Tyr 29 - Gln 159 | |
| TSLP | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >85% as determined by SDS-PAGE |
| 18.6 kDa | |
| Biotinylated Human TSLP, His,Avitag (TSP-H82Eb) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # Q969D9-1). | |
| -20°C | |
| TSLP | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |