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ACROBiosystems Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag

Recommended for biopanning

Brand:  ACROBiosystems PD2-H82E8-25UG

Additional Details : Weight : 0.00001kg

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Product Code. 15807517

  • 353.08€ / 25µg


Estimated Shipment: 19-10-2021
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Description

Description

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.2 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

AAI13679
HEK293
Human
25.2 kDa
25 µg
Leu 20 - Pro 219
PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human PD-L2, Avitag,His Tag (recommended for biopanning) (PD2-H82E8) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679).
-20°C
PD-L2
His Tag and Avi Tag
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