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ACROBiosystems Biotinylated Human IL-17 RA / CD217 Protein, Fc, Avitag™

Biotinylated Protein

Brand:  ACROBiosystems ILA-H82F1-200UG

Additional Details : Weight : 0.00001kg

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Product Code. 15817087

  • 1392.13€ / 200µg


Estimated Shipment: 22-10-2021
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Description

Description

Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 61.9 kDa. As a result of glycosylation, the protein migrates as 80-115 kDa under reducing (R) condition, and 150-200 kDa under
Specifications

Specifications

NP_055154.3
HEK293
Human
61.9 kDa
200 µg
Leu 33 - Trp 320
CD217,CDw217,IL-17 RA,IL17R,CANDF5,hIL-17 R
Precision Avi
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human IL-17 RA, Fc,Avitag (ILA-H82F1) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).
-20°C
IL-17 RA
Fc Tag and Avi Tag
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