Ly-6C Rat anti-Mouse, FITC, Clone: AL-21, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 561085
Additional Details : Weight : 0.01000kg
The AL-21 monoclonal antibody specifically binds to a non-polymorphic determinant of Ly-6C, a 14-17 kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells.Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described,and Ly-6C is a memory marker on CD8+ T cells.
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
For Research Use Only.