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IL-17A Rat anti-Mouse, Alexa Fluor 488, Clone: TC11-18H10, BD

Rat Monoclonal Antibody

Brand:  BD Biosciences 560221

Additional Details : Weight : 0.01000kg

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Product Code. 15820029

  • 212.00€ / Each


Estimated Shipment: 07-10-2021
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Description

Description

The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8-thymocytes.

Host Species: Rat
Clone: TC11-18H10
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Recombinant Mouse IL-17A Protein

Intracellular Staining

Specifications

Specifications

IL-17A
TC11-18H10
Alexa Fluor 488
Affinity Purified
Recombinant Mouse IL-17 Protein
25μg
Immunology
Primary
Murine
Flow Cytometry
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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For Research Use Only.