CD64 Mouse anti-Human, PE, Clone: 10.1, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 561926
Additional Details : Weight : 0.00870kg
The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Human rheumatoid synovial fluid cells and fibronectin-purified monocytes|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.