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HRD1 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA534233
Additional Details : Weight : 0.01000kg
Description
HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.Specifications
| HRD1 | |
| Polyclonal | |
| Unconjugated | |
| SYVN1 | |
| Liquid | |
| SYVN1 | |
| Synthetic 18 amino acid peptide from internal region of human SYVN1 / HRD1. | |
| Antigen affinity chromatography | |
| RUO | |
| Antibody | |
| Polyclonal | |
| Human |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| PBS with < 0.1% sodium azide | |
| Q86TM6 | |
| SYVN1, KIAA1810, Synoviolin, Synovial apoptosis inhibitor 1, DER3, HRD1 | |
| Rabbit | |
| IgG | |
| 50 μg | |
| Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C | |
| Primary | |
| 84447 |