missing translation for 'onlineSavingsMsg'
Learn More

Glucocorticoid Receptor Mouse anti-Human, Unlabeled, Clone: 41, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 611227

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15825849

  • 690.00€ / 1 set
Estimated Shipment: 23-04-2024
to see stock.
Add to basket

Description

Description

Steroid hormone receptors are hormone activated transcriptional regulators that influence genes required for embryonic development and adult homeostasis. One member of the steroid hormone family is the glucocorticoid receptor. It contains AF1 and AF2 transactivation domains, a DNA binding domain, and ligand binding domain. Ligand bound glucocorticoid receptors dimerize at specific palindromic sequences called glucocorticoid response elements (GREs) in the cis-regulatory region of target genes. Both AF1 and AF2 may be important for initiation or regulation of transcription by interacting with components of the initiation complex or other intermediary factors. In addition to transactivation, glucocorticoid receptors may also regulate transcription through transrepression of target genes. Although mechanisms of transrepression are not completely understood; DNA binding alone, DNA binding plus interaction with other transcription factors, or protein-protein interaction without DNA binding are mechanisms that have been implicated. Thus, glucocorticoid receptors function in the
regulation of specific genes that are essential for human development and homeostasis.

Host Species: Mouse
Clone: 41
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Glucocorticoid Receptor α aa. 176-289
Formula Weight [Chemical]: 94kDa

Immunofluorescence, Western Blotting

Specifications

Specifications

Glucocorticoid Receptor
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human Glucocorticoid Receptor α aa. 176-289
150 μg
Cell Biology
Human
IgG1
Western Blot
41
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only.