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CD95 Mouse, Unlabeled, Clone: 13, BD

Mouse Monoclonal Antibody

629.00€

Specifications

Antigen CD95
Clone 13
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
15835329
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BD Biosciences
610198
150 μg This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on +351 21 425 33 50 for assistance
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Description

Description

CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene.

Specifications

Specifications

CD95
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
Fas, APO-1
13
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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Product Certifications

For Research Use Only.