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CD62P Mouse anti-Human, Brilliant Violet 786, Clone: AK-4, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 563715

Additional Details : Weight : 0.01000kg

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Product Code. 15823029

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Description

Description

The AK-4 monoclonal antibody specifically binds to CD62P. CD62P is a 140 kDa type I transmembrane glycoprotein that is also known as P-Selectin, Platelet activation-dependent granule membrane protein (PADGEM), or GMP-140. P-Selectin is stored in the α-granules of platelets and the Weibel-Palade bodies of endothelial cells, and is rapidly transported to the plasma membrane upon activation. P-Selectin is thought to mediate the initial adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses, and of activated platelets to neutrophils and monocytes in hemostasis.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

Specifications

CD62P
Monoclonal
Brilliant Violet 786
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
AK-4
P-Selectin; GMP-140; PADGEM
Mouse
100 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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For Research Use Only.