missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD38 Mouse anti-Human, BB515, Clone: HIT2, BD
Mouse Monoclonal Antibody
215.00€ - 401.00€
Specifications
| Antigen | CD38 |
|---|---|
| Clone | HIT2 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | Brilliant Blue 515 (BB515) |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15823689
|
BD Biosciences
564499 |
25 Tests |
215.00€
Each |
Estimated Shipment: 15-05-2024
Log in to see stock. |
|||||
|
15813689
|
BD Biosciences
564498 |
100 Tests |
401.00€
Each |
Estimated Shipment: 06-05-2024
Log in to see stock. |
|||||
Description
The HIT2 monoclonal antibody specifically binds to CD38. The CD38 antigen is also known as T10, ADP-ribosyl cyclase 1, and cyclic ADP ribose hydrolase 1. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells and terminally differentiated B cells (plasma cells). CD38 is expressed by other cells including monocytes, macrophages, dendritic cells, NK cells, myeloid and erythroid precursors and some epithelial cells. The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signaling pathways leading to cellular growth, apoptosis, and differentiation. CD38 binds to CD31 and thus plays a role in lymphocyte adhesion to endothelial cells.
The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.
Specifications
| CD38 | |
| Flow Cytometry | |
| Brilliant Blue 515 (BB515) | |
| RUO | |
| IgG1 κ | |
| Affinity Purified | |
| T10; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1 |
| HIT2 | |
| Monoclonal | |
| Mouse | |
| Human | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.