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CD34 Mouse anti-Human, FITC, Clone: 581, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 555821

Additional Details : Weight : 0.02000kg

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Product Code. 15808468

  • 289.00€ / Each


Estimated Shipment: 06-10-2021
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Description

Description

The 581 monoclonal antibody specifically binds to CD34, a sialomucin-like type I transmembrane glycoprotein. This single-chain, 105-120 kDa, heavily O-glycosylated protein is expressed on hematopoietic progenitor cells, vascular endothelium, bone marrow stromal cells and embryonic fibroblasts. The cytoplasmic region of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting CD34 may play a role in signal transduction. CD34 may also play a role as an adhesion molecule since it binds to CD62E and CD62L. Clone 581 binds to the class III CD34 epitope, it is resistant to neuraminidase, chymopapain and glycoprotease. The 581 antibody blocks reactivity of another anti-CD34 monoclonal antibody, 8G12.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

CD34
581
gp105-120; My10; Hematopoietic progenitor cell antigen CD34
Affinity Purified
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse
100 Tests
Immunology
Primary
Human
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For Research Use Only.