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CD3 Mouse anti-Human, FITC, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 561807

Additional Details : Weight : 0.02180kg

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Product Code. 15821359

  • 1565.00€ / Each
Estimated Shipment: 23-04-2024
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Description

Description

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Specifications

Specifications

CD3
Monoclonal
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
500 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
UCHT1
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Mouse
Affinity Purified
RUO
Human
IgG1 κ
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