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CD274 Mouse anti-Human, PE, Clone: MIH1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 561787

Additional Details : Weight : 0.02000kg

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Product Code. 15821339

  • 165.00€ / Each


Estimated Shipment: 06-10-2021
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Description

Description

PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells, including IFN- γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2 on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts, myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.

Specifications

Specifications

CD274
MIH1
B7-H1, PD-L1
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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For Research Use Only.