missing translation for 'onlineSavingsMsg'
Learn More

CD25 Mouse anti-Human, Brilliant Violet 421, Clone: M-A251, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 562443

Additional Details : Weight : 0.00800kg

 View more versions of this product

Product Code. 15811929

  • 255.00€ / Each


Estimated Shipment: 06-10-2021
Add to basket

Description

Description

The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses. The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Host Species: Mouse
Clone: M-A251
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

Specifications

Specifications

CD25
M-A251
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
Brilliant Violet 421
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
SDS
Documents
Certificates

For Research Use Only.