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CD25 Mouse anti-Human, Brilliant Violet 421, Clone: M-A251, BD
Mouse Monoclonal Antibody
326.00€ - 725.00€
Specifications
| Antigen | CD25 |
|---|---|
| Clone | M-A251 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | Brilliant Violet 421 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15811929
|
BD Biosciences
562443 |
25 Tests |
326.00€
Each |
Estimated Shipment: 22-05-2024
Log in to see stock. |
|||||
|
15801929
|
BD Biosciences
562442 |
100 Tests |
725.00€
Each |
Estimated Shipment: 14-05-2024
Log in to see stock. |
|||||
Description
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses. The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Host Species: Mouse
Clone: M-A251
Isotype: IgG1, κ
Species Reactivity: Human
Flow Cytometry
Specifications
| CD25 | |
| Flow Cytometry | |
| Brilliant Violet 421 | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| M-A251 | |
| Monoclonal | |
| Mouse | |
| Human | |
| IgG1 κ | |
| Affinity Purified | |
| IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 |
For Research Use Only.