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CD2 Rat anti-Mouse, FITC, Clone: RM2-5, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 553111
Additional Details : Weight : 0.01000kg
Description
The RM2-5 monoclonal antibody specifically binds to the immunoglobulin superfamily adhesion molecule, CD2 (LFA-2). CD2 is a type I transmembrane glycoprotein that serves as the the major receptor for CD48 in the mouse. CD2 is involved in T-cell activation, immunoregulation, and thymocyte maturation. In the mouse, CD2 is expressed on peripheral T lymphocytes, B lymphocytes, and NK cells, and a subpopulation of intraepithelial T lymphocytes. CD2 is expressed throughout mouse thymic ontogeny, except for distinct subsets of the CD4-CD8- early thymocytes. In the mouse bone marrow, CD2 is expressed on B220+ sIg+ CD43- pre-B cells, but not on CD43+ pro-B cells. The RM2-5 antibody is one of a set of five anti-mouse CD2 monoclonal antibodies that were classified into two groups according to their mutual competition in binding to cell surface CD2 and which block CD2-mediated cell-cell adhesion.
Specifications
| CD2 | |
| Monoclonal | |
| 0.5mg/mL | |
| LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; T11 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| RM2-5 | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse BALB/c Thymocytes | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG2b λ |
For Research Use Only.