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CD19 Mouse anti-Human, BB515, Clone: HIB19, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 564456

Additional Details : Weight : 0.01000kg

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Product Code. 15823659

  • 468.00€ / Each
Estimated Shipment: 16-04-2024
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Description

Description

The HIB19 monoclonal antibody specifically binds to the 95 kDa type I transmembrane CD19 glycoprotein. CD19 is expressed during all stages of B-cell maturation and differentiation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 is a signal transduction molecule that regulates B cell development, activation, proliferation and differentiation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks the binding of clone B43, another CD19-specific monoclonal antibody.

The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g., 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Specifications

Specifications

CD19
Monoclonal
Brilliant Blue 515 (BB515)
Mouse
100 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
HIB19
B4; B-lymphocyte antigen CD19; Leu-12
Affinity Purified
RUO
Human
IgG1 κ
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