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CD146 Mouse anti-Human, PE, Clone: P1H12, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 561013

Additional Details : Weight : 0.01000kg

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Product Code. 15810689

  • 190.00€ / Each
Estimated Shipment: 23-04-2024
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Description

Description

The P1H12 monoclonal antibody specifically binds to CD146. CD146 is a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, or Mel-CAM. CD146 is a member of the immunoglobulin superfamily and is expressed by angioblasts and mesenchymal stems cells and is strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also expressed by melanoma cells, intermediate trophoblasts and a subpopulation of activated T cells. The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion that is observed very early in embryogenesis. It can be useful in the study of embryologic vasculogenesis. This antibody is suitable for immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA.

Specifications

Specifications

CD146
Monoclonal
PE
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
P1H12
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human Umbilical Vein Cells
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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For Research Use Only.