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CD11b Rat anti-Mouse, V450, Clone: M1/70, BD
Rat Monoclonal Antibody
202.00€ - 445.00€
Specifications
| Antigen | CD11b |
|---|---|
| Clone | M1/70 |
| Concentration | 0.2mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15820219
|
BD Biosciences
560456 |
25 μg |
202.00€
Each |
Estimated Shipment: 07-05-2024
Log in to see stock. |
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|
15810219
|
BD Biosciences
560455 |
0.1 mg |
445.00€
Each |
Estimated Shipment: 13-05-2024
Log in to see stock. |
|||||
Description
The M1/70 antibody reacts with the 170kDa α(M) chain of Mac-1 (CD11b/CD18, α(M)β(2) integrin), also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 cells. Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. M1/70 antibody reportedly blocks cell adherence and C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported.
Host Species: Rat
Clone: M1/70
Isotype: IgG2b, κ
Species Reactivity: Mouse
Immunogen: Mouse splenic Cells
Flow Cytometry
Specifications
| CD11b | |
| 0.2mg/mL | |
| Monoclonal | |
| Rat | |
| Immunology | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| IgG2b κ | |
| Affinity Purified | |
| Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain |
| M1/70 | |
| Flow Cytometry | |
| Violet Fluor 450 (V450) | |
| RUO | |
| Human, Mouse | |
| Mouse splenic Cells | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.