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CCR6 Mouse anti-Human, Clone: 53103.111, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA120156

Additional Details : Weight : 0.01000kg

Product Code. 11543753

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on +351 21 425 33 50 for assistance


Description

Description

MA1-20156 detects CCR6 in human samples. MA1-20156 has been successfully used in FACS and immunohistochemistry (frozen) procedures. The MA1-20156 immunogen is human CCR6 transfected NSO mouse myeloma cells. Endotoxin level is less than 10 ng per mg antibody as determined by the LAL method.

Chemokines have been sub-divided into families on the basis of the relative position of their cysteine residues. The a- and b- families, with four cysteine residues, are the largest and best characterized. CCR-6 (previously referred to as the GPR-CY4, CKRL3, or STRL22 orphan receptor) binds MIP-3". It is a CC chemokine receptor that is highly expressed in human dendritic cells derived from CD34+ cord blood precursors.2-4 In addition to dendritic cells, CCR-6 mRNA has also been detected in lymphocytes (CD4 and CD8 T cells and B cells), but not in natural killer cells, monocytes and granulocytes.
Specifications

Specifications

CCR6
Monoclonal
0.5 mg/mL
CCR6
BN-1, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22
Mouse
Protein G
RUO
1235
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Flow Cytometry, Immunohistochemistry (Frozen)
53103.111
Unconjugated
P51684
CCR6
Human CCR6 transfected NSO mouse myeloma cells.
100 μg
Primary
Human
Antibody
IgG2b
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