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Tocris Bioscience™ ACHP
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Product Code. 30001611
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 30001611

Brand: Tocris Bioscience™ 4547/10

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This item is not returnable. View return policy

Description

Selective IKKα and IKKβ inhibitor

IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively). Selective for IKKα and IKKβ over IKK3, Syk and MAPKKK4 (IC50 values are > 20 μM). Inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

CAS 406208-42-2
Quantity 10 mg
Molecular Formula C21H24N4O2
Formula Weight 364.44
Purity >97%
Molecular Weight (g/mol) 364.449
Chemical Name or Material ACHP
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